500 W Onondaga Street

Exceptional opportunity to own a storied Syracuse landmark on the revitalized West Onondaga corridor. This well-cared-for, 3.5-story Queen Anne Victorian pairs timeless architectural detail—original hand-carved woodwork, custom ironwork, and high ceilings—with modern mechanical updates, including updated heating, cooling, and plumbing. The versatile ~6,372 sq. ft. layout features 13 adaptable office/treatment rooms, 4 bathrooms (2 with showers), and a stunning 1930s chapel expansion that provides an expansive open-concept venue for events, studios, or wellness concepts. A full basement and usable attic space offer abundant storage and growth potential. Unmatched urban convenience with 19 off-street parking spaces, an accessible entrance ramp, and a detached 4-car garage on a generous 0.68-acre parcel. Perfectly suited for an owner-occupant, boutique professional/medical or attorney firm, or signature mixed-use investment. Located within a federal Qualified Opportunity Zone with potential Historic Tax Credit eligibility. Schedule your tour today by emailing a request to consultdamianihomes@gmail.com.