643 Grand Avenue South San Francisco, CA $ 1,248,000
643 Grand Avenue
$ 1,248,000
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643 Grand Avenue

South San Francisco, CA, 94080
$ 1,248,000
Bedrooms3 Baths4.0 Sq 1,630

Monthly Estimate*

$ 7,880

Listed by Christie's International Real Estate Sereno
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Single Family Home for sale in South San Francisco, CA

for $1,248,000 with 3 bedrooms and 4 full baths. This 1,630 square foot home was built in 1895 on a lot size of 0.0803.

Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging. The home also features a water purification system, tankless water heater, and water softener. The quaint lot includes a freshly manicured organic vegetable garden with sunflowers and offers potential for an ADU. Conveniently located near Downtown South San Francisco, Genentech, Caltrain, US-101, and I-280.

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Single Family Active

Price

$ 1,248,000

Bedrooms

3

Full Bath

4

Property Type

Single Family

Taxes

$ 0

Style

Lot Size

0.0803

Year Built

1895

Town/City

South San Francisco

County/Region

San Mateo

MLS | Web ID

ML82059314

Days on Market

2

Features
General
Living Area 1630
Sewer Public Sewer
Heating Central
Cooling None
Roof Shingle
Zoning RM0000
Garage Spaces 2
Year Built 1895
Property Subtype Single Family Residence
County San Mateo
New Construction false
Property Type Residential
HOA false
Attached Garage false
Garage Y/N true
Full Baths 4
Special Listing Conditions Standard
Status Active
Directions Cross Street: Orange Avenue
City South San Francisco
High School District South San Francisco Unified
MLS Area 699 - Not Defined
Lot Size Units Square Feet
Lot Size Square Feet 3500
Property Attached Y/N false
Standard Status Active
Occupancy Type Vacant
Year Built Source Assessor
Property Sub Type Additional Single Family Residence
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Interior
Total Stories 2
Common Walls No Common Walls
Air Conditioning Y/N true
Heating Y/N true
Window Features Skylight(s)
Fireplace Y/N false
Total Bedrooms 3
Total Baths 4
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Exterior
Water Source Public
Total Parking 2
Lot Size Area 3500
Foundation Details Slab
Lot Size Acres 0.0803
Lot Size Source Assessor
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* Excluded Features
List By
Christie's International Real Estate Sereno

Broker

jill@jillpenna.com

Email

Affordability Calculator

$7,880
Per Month
100%
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Monthly Principal & Interest
$7,880
Monthly Property Taxes
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Monthly Home Insurance
--
Default based on a 30-year fixed rate of 6.49% with 20% down. The estimated payment is offered for convenience and is not an offer of credit. Due to market fluctuations, interest rates are subject to change at any time and without notice. Your individual rate may vary. Rates may differ for FHA, VA or jumbo loans.
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Nearby
4827338 Elementary School
4827337 Middle School
Unknown High School High School
Pricing History
DatePricePrice ChangeDescription
8/28/2026$1,248,000 Listed Price

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643 Grand Avenue, South San Francisco, CA, 94080 is a Single Family Home for sale at $1,248,000 with 1,630 sqft and a lot size of 0.0803. 643 Grand Avenue has 3 bedrooms, 4.0 baths, and was built in 1895. The property's zip code is 94080 which is in South San Francisco, CA