110 E Greenville Street
Anderson, SC, 29621 $ 2,300,000
Bedrooms-- Baths-- for $2,300,000. The lot size is 1.21.
Endless investment potential on one of Anderson's most iconic corners! Nestled in one of Anderson’s most prominent and well-trafficked locations, this multi-building, multi-tenant portfolio property offers an unparalleled opportunity for business owners and investors alike. Occupying nearly half of one of the city’s most iconic blocks, this property is a cornerstone of Anderson’s bustling commercial hub. Its strategic location at the intersection of E Greenville Street and Main Street ensures maximum visibility and accessibility, making it an ideal destination for retail, professional services, or dining establishments. Spanning 1.21 acres with over 14,000 square feet of versatile space, the property features multiple buildings designed to accommodate a range of commercial needs. Positioned at the corner of E Calhoun and McDuffie Streets, the site also enjoys frontage along E Greenville Street, with red-light access on three sides to ensure seamless traffic flow for patrons and clients. The property’s layout offers flexibility, allowing tenants to customize the spaces to suit their specific requirements, whether they are a retail vendor, restaurateur, or professional office provider. The visibility and accessibility of this property are unmatched. Its location within the heart of Anderson places it amidst thriving businesses, providing a steady stream of potential customers. The property’s position on key city streets ensures consistent exposure to both pedestrian and vehicle traffic, making it a highly desirable site for a range of ventures. Whether you’re looking to establish a flagship retail store, expand a professional office portfolio, or create a dining destination in one of South Carolina’s fastest-growing cities, this property offers the space, location, and flexibility needed to bring your vision to life. With its prime location and multi-tenant potential, this commercial listing is a rare opportunity to secure a presence in the heart of Anderson’s vibrant economic landscape. Don’t miss your chance to be part of this thriving community.
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FeaturesGeneralSewer Public Sewer
Heating Natural Gas
Cooling Electric
Roof Other
Construction Materials Block Brick
Topography Level
Property Subtype Retail
Tax Year 2024
Business Type Health Services Professional/Office Professional Service Restaurant Retail
County Anderson
New Construction N
Property Type Commercial Sale
HOA N
Attached Garage N
Garage Y/N N
Building Features Loading Dock
Rent Includes None
Status Active
Directions Interstate 85 to exit 27 towards Anderson. Follow the 4 lane highway to main street and property will be on the left before red light.
City Anderson
Senior Community Y/N N
MLS Area 053
Lot Size Units Acres
Lot Size Square Feet 52707.6
Carport Y/N N
Tax Annual Amount 17722
Property Condition 50+
Lease Considered Y/N N
Building Area Units Square Feet
Lease Type Other/See Remarks
Living Area Units Square Feet
Standard Status Active
Occupancy Type Tenant
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InteriorFlooring Carpet Concrete Slab/Grade Linoleum
Basement (Y/N) N
Air Conditioning Y/N Y
Heating Y/N Y
Window Features Display Window(s)
Fireplace Y/N N
Below Grade Finished Area Unit Type Square Feet
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ExteriorWater Source Public
Lot Size Area 1.21
Spa N
Lot Size Acres 1.21
Waterfront Y/N N
Road Frontage Type City Street Other
Horse Y/N N
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* Excluded FeaturesList BySherry L TraynumListing Agent
Howard Hanna Allen Tate/Pine To Palm RealtyBroker
sherry@p2prealty.netEmail
NearbyAbout Anderson, SC 27,579 Population
10% Since 2002
$ 36,651 Median Income
37.36 Median Age
28% Households with Children
Trends Information provided by ATTOM Data Solutions.
331300 Elementary School
331424 Middle School
Unknown High School High School
Pricing History| Date | Price | Price Change | Description |
|---|
| 6/11/2026 | $2,300,000 | -2.13% | Price Down |
| 6/11/2026 | $2,350,000 | | Listed Price |