1250 MCDUFF Avenue S

FOR LEASE - 2,400 SQFT COMMERCIAL OR MIXED-USE SPACE in the Riverside Avondale Historic District. Rare opportunity to lease approximately 2,400 square feet of versatile commercial or mixed-use space in the heart of Jacksonville's highly sought-after Riverside Avondale neighborhood. Located within one of the area's few Commercial Neighborhood (CN) zoning districts, the property allows for a wide variety of permitted uses including professional or medical office, wellness or fitness studio, retail sales, service establishments, creative office, salon, counseling practice, and more. BUILDING IS ALSO FOR SALE -- ASK ABOUT OWNER FINANCING! Use the whole building for your business or run your business on the 1st floor and rent the second floor residential apartment to offset your expenses! The space was previously occupied by a long-term Pilates studio and offers a functional layout with excellent natural light, strong visibility, and a move-in-ready interior. Positioned just minutes from the Avondale and King Street shopping districts, Willowbranch Park, and the St. Johns River, this location benefits from strong neighborhood demographics, walkability, and proximity to some of Jacksonville's most established residential communities. Lease Terms * Approximately 2,400 SQFT * Asking Rate: $16.00 PSF Gross * Separately metered utilities for each floor *Rear parking available * Zoned Commercial Neighborhood (CN) Ideal for: Boutique fitness " Wellness " Professional office " Medical office " Counseling " Salon/Spa " Creative studio " Specialty retail " Service-based businesses Rare small-format commercial or mixed-use opportunity in one of Jacksonville's most desirable urban neighborhoods.