Located in the heart of downtown Bay St. Louis, this gateway to Main Street is an iconic modern mixed-use property offering exceptional design, efficiency, and flexibility. Situated on high ground at the prominent triangular lot formed by Main Street, Old Spanish Trail, and Dunbar Avenue, this distinctive site did not flood during Hurricane Katrina. The site was originally developed circa 1890 and thoughtfully reimagined in 2010 with construction designed to LEED-Gold environmental standards. The approximately 0.226-acre C-2 zoned property features a 2,172± SF large commercial space, a 405± SF smaller commercial suite, and a 970± SF one-bedroom loft residence, for a total of 3,547 SF, along with nine on-site parking spaces including one accessible space. The primary commercial space is a beautifully finished one-story structure with cypress and corrugated metal exterior, high-performance building envelope, insulated aluminum-clad wood windows, and energy-efficient systems designed to use approximately 70% less energy than baseline standards. Interior features include an open studio workspace with custom millwork for up to 13 desks, conference room, kitchen, copy room, full bath with shower, and storage loft. Finishes include gypsum board, cypress paneling, bamboo flooring, carpet tile, beaded board ceilings, and PaperStone work surfaces crafted from recycled paper and cashew resin. Lighting and climate control systems are designed for comfort, efficiency, and abundant natural light throughout. Both commercial spaces are accessible via ramps. A separate 405± SF commercial suite offers its own entrance, prominent corner display window, concrete floors, powder room, ductless mini-split HVAC, and flexible layout suitable for retail, gallery, or office use. The residential component features a striking two-story loft with expansive corner windows overlooking Main Street and Dunbar Avenue, a full kitchen, fully tiled bath, sliding barn-door closet, in-unit washer/dryer, private balcony, and roof terrace access. Finishes include bamboo and laminate wood flooring, wood stairs, and bright daylight in every room. Additional features include automated lighting controls, rainwater harvesting cistern, variable air volume HVAC in the main office, and room for future development along the Dunbar Avenue frontage, currently landscaped with seasonal flowers. Available documents include a survey, geotechnical report, and architectural plans. This architecturally significant property offers a rare opportunity to live, work, and invest in one of the Gulf Coast's most distinctive mixed-use environments.