422 21st Street
Denver, CO, 80205 $ 1,100,000
Bedrooms4 Baths2.0 Sq 2,565 Monthly Estimate*
$ 6,946
Listed by Kentwood Commercial, Llc
for $1,100,000 with 4 bedrooms and 2 full baths. This 2,565 square foot home was built in 1886 on a lot size of 0.14.
Rare and storied mixed-use opportunity situated on a highly visible 6,270-square-foot corner lot in the heart of Five Points. The property features a historic five-bedroom residence and a separate office building, totaling approximately 6,565 square feet of improvements on a single parcel. Ideally positioned just steps from Benedict Fountain Park, the RTD 27th & Welton Light Rail Station, neighborhood coffee shops and restaurants, and only minutes from Downtown Denver and Uptown, the property offers an exceptional blend of urban convenience, historic character, and neighborhood connectivity. The property includes an approximately 2,565-square-foot historic residence with five bedrooms and two bathrooms, currently operating as a successful Airbnb and providing immediate income or the opportunity for owner occupancy. Tucked behind the residence is a rare, private rear patio, offering an inviting outdoor retreat ideal for entertaining, relaxing, or complementing a live/work lifestyle—an uncommon amenity for a property so close to downtown. Complementing the residence is a separate office duplex totaling approximately 4,000 square feet, comprised of two approximately 2,000-square-foot office suites, one of which is currently leased on a month-to-month basis, providing immediate cash flow while preserving flexibility for future occupancy, repositioning, or redevelopment. Located within the Clements Historic District, this unique property offers exceptional visibility, walkability, and access to some of Denver’s most desirable dining, entertainment, cultural, and transit amenities. Whether envisioned as an investment, corporate headquarters with supplemental income, creative office campus, live/work environment, boutique hospitality concept, or long-term repositioning opportunity, this one-of-a-kind asset presents remarkable versatility in one of Denver’s most vibrant and historically significant neighborhoods.
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FeaturesGeneralSewer Public Sewer
Heating Hot Water
Cooling None
Roof Composition
Zoning C-MX-5
Garage Spaces 0
Construction Materials Brick
Exclusions Personal Property.
Year Built 1886
Levels Two
Property Subtype Single Family Residence
Tax Year 2024
Ownership Individual
County Denver
Property Type Residential
HOA N
Attached Garage N
Subdivision Name Five Points
Full Baths 1
Status Active
High School East
City Denver
Senior Community Y/N N
High School District Denver 1
Lot Size Units Square Feet
Lot Size Square Feet 6270
Carport Spaces 0
Listing Terms Cash Conventional
Elementary School Whittier E-8
Tax Annual Amount 15636
Middle/Junior High School Cole Arts And Science Academy
Structure Type House
Standard Status Active
Middle/Junior School District Denver 1
Elementary School District Denver 1
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ExteriorLot Features Level
Total Parking 0
Lot Size Area 6270
Building Area Total 2565
Lot Size Acres 0.14
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InteriorBasement (Y/N) N
Above Grade Finished Area 2565
Half Baths 0
1/4 Baths 0
3/4 Baths 1
Total Bedrooms 4
Main Level Bedrooms 1
Main Level Bathrooms 1
Total Baths 2
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* Excluded FeaturesList ByKentwood Commercial, LlcBroker
Affordability Calculator
- Monthly Principal & Interest
- $6,946
- Monthly Property Taxes
- $1,303
- Monthly Home Insurance
- --
Default based on a 30-year fixed rate of 6.49% with 20% down. The estimated payment is offered for convenience and is not an offer of credit. Due to market fluctuations, interest rates are subject to change at any time and without notice. Your individual rate may vary. Rates may differ for FHA, VA or jumbo loans.
Learn more about how to save NearbySingle family listings in Denver, CO
Average List Price $968,282
Percent of Sale Price 12%
About Denver, CO 24,748 Population
9% Since 2002
$ 36,940 Median Income
38.83 Median Age
13% Households with Children
Trends Information provided by ATTOM Data Solutions.
3043902 Elementary School
4182973 Middle School
East High School High School
Pricing History| Date | Price | Price Change | Description |
|---|
| 7/24/2026 | $1,100,000 | -4.35% | Price Down |
| 6/24/2026 | $1,150,000 | -4.17% | Price Down |
| 3/23/2026 | $1,200,000 | -4.00% | Price Down |
| 2/10/2026 | $1,250,000 | | Listed Price |