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376 Main St Barnstable, MA ^$ 2,250

376 Main St

^$ 2,250

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Recently Listed

376 Main St

Barnstable, MA, 02601

^$ 2,250

Bedrooms-- Baths-- Sq 1,300

376 Main St, Barnstable, MA 02601 - Image 1

376 Main St, Barnstable, MA 02601 - Image 2

376 Main St, Barnstable, MA 02601 - Image 3

376 Main St, Barnstable, MA 02601 - Image 4

376 Main St, Barnstable, MA 02601 - Image 5

376 Main St, Barnstable, MA 02601 - Image 6

Property for Rent in Barnstable, MA

for $2,250. This 1,300 square foot property was built in 1944 on a lot size of 0.89.

Now available for lease, this ±1,300 SF ground-floor retail space at 376 Main Street offers a rare opportunity to establish your business in one of Hyannis’ most active and desirable commercial corridors. Positioned along bustling Main Street, this location delivers excellent visibility, strong foot traffic, and outstanding signage exposure.This move-in ready space features a modern, high-end interior buildout, making it ideal for boutique retail, specialty services, or professional users seeking a polished customer-facing environment.

Rental Active

Price

^$ 2,250

Taxes

^$ 10,780

Style

Professional/Office

Lot Size

0.89

Year Built

1944

Town/City

Barnstable

County/Region

Barnstable

MLS | Web ID

73489036

List By

Kevin A. Pepe

Listing Agent

Commercial Realty Advisors, Inc.

Broker

Nearby

Trends

About Barnstable, MA

45,501 Population

-5% Since 2002

^$64,834 Median Income

49.53 Median Age

21% Households with Children

View more area information

Trends Information provided by ATTOM Data Solutions.

Neighborhood & Schools

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Pricing History

Date	Price	Price Change	Description
3/19/2026	$2,250		Listed Price

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376 Main St, Barnstable, MA, 02601 is a Property for Rent at $2,250 with 1,300 sqft and a lot size of 0.89. 376 Main St was built in 1944. The property's zip code is 02601 which is in Barnstable, MA

*Information deemed reliable but not guaranteed.

Financial calculator disclaimer: Default based on a 30-year fixed rate of 6.25% with 20% down. The estimated payment is offered for convenience and is not an offer of credit. Due to market fluctuations, interest rates are subject to change at any time and without notice. Your individual rate may vary. Rates may differ for FHA, VA or jumbo loans.

Data is updated as of 3/30/2026.

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The property listing data and information, or the Images, set forth herein were provided to MLS Property Information Network, Inc. from third party sources, including sellers, lessors and public records, and were compiled by MLS Property Information Network, Inc. The property listing data and information, and the Images, are for the personal, non-commercial use of consumers having a good faith interest in purchasing or leasing listed properties of the type displayed to them and may not be used for any purpose other than to identify prospective properties which such consumers may have a good faith interest in purchasing or leasing. MLS Property Information Network, Inc. and its subscribers disclaim any and all representations and warranties as to the accuracy of the property listing data and information, or as to the accuracy of any of the Images, set forth herein.

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376 Main St

Property for Rent in Barnstable, MA

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