110 E Greenville Street Anderson, SC $ 2,350,000
110 E Greenville Street
$ 2,350,000
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110 E Greenville Street

Anderson, SC, 29621
$ 2,350,000
Bedrooms-- Baths--

Monthly Estimate*

$ 14,661

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Commercial Property for sale in Anderson, SC

for $2,350,000. The lot size is 1.21.

Endless investment potential on one of Anderson's most iconic corners! Nestled in one of Anderson’s most prominent and well-trafficked locations, this multi-building, multi-tenant portfolio property offers an unparalleled opportunity for business owners and investors alike. Occupying nearly half of one of the city’s most iconic blocks, this property is a cornerstone of Anderson’s bustling commercial hub. Its strategic location at the intersection of E Greenville Street and Main Street ensures maximum visibility and accessibility, making it an ideal destination for retail, professional services, or dining establishments. Spanning 1.21 acres with over 14,000 square feet of versatile space, the property features multiple buildings designed to accommodate a range of commercial needs. Positioned at the corner of E Calhoun and McDuffie Streets, the site also enjoys frontage along E Greenville Street, with red-light access on three sides to ensure seamless traffic flow for patrons and clients. The property’s layout offers flexibility, allowing tenants to customize the spaces to suit their specific requirements, whether they are a retail vendor, restaurateur, or professional office provider. The visibility and accessibility of this property are unmatched. Its location within the heart of Anderson places it amidst thriving businesses, providing a steady stream of potential customers. The property’s position on key city streets ensures consistent exposure to both pedestrian and vehicle traffic, making it a highly desirable site for a range of ventures. Whether you’re looking to establish a flagship retail store, expand a professional office portfolio, or create a dining destination in one of South Carolina’s fastest-growing cities, this property offers the space, location, and flexibility needed to bring your vision to life. With its prime location and multi-tenant potential, this commercial listing is a rare opportunity to secure a presence in the heart of Anderson’s vibrant economic landscape. Don’t miss your chance to be part of this thriving community.

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Commercial Active

Price

$ 2,350,000

Property Type

Commercial

Taxes

$ 13,100

Style

Retail

Lot Size

1.21

Town/City

Anderson

County/Region

Anderson

MLS | Web ID

20282299

Features
General
Heating Central Gas
Cooling CentralAir Electric
Utilities CableAvailable ElectricityAvailable NaturalGasAvailable PhoneAvailable SewerAvailable WaterAvailable
Possession CloseOfEscrow
Roof Metal
Construction Materials Brick
Stories Count 1
Topography Level
Levels One
Property Subtype Retail
Tax Year 2024
Business Type Dental Medical ProfessionalOffice ProfessionalService Restaurant Warehouse
Additional Parcels Description 1232921005
County Anderson
New Construction N
Property Type CommercialSale
HOA N
Attached Garage N
Garage Y/N N
Building Features LoadingDock
Status Active
Directions Interstate 85 to exit 27 towards Anderson. Follow the 4 lane highway to main street and property will be on the left before red light.
City Anderson
Senior Community Y/N N
MLS Area 101-Anderson County SC
Lot Size Units Acres
Carport Y/N N
Year Built Details Over 25 Years
Land Lease Y/N N
Tax Annual Amount 13100.0
Home Warranty Y/N N
Lease Renewal Y/N N
Additional Parcels Y/N N
Lease Considered Y/N N
Rent Control Y/N N
Standard Status Active
Occupancy Type Owner
TaxOtherAnnualAssessmentAmount 4622.0
Property Sub Type Additional Retail
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Exterior
Exterior Amenities Other
Lot Features CityLot Level
Lot Size Area 1.21
Spa N
Lot Size Acres 1.21
Other Parking 26 - 99
Waterfront Y/N N
Road Frontage Type CityStreet Highway
Crops Included Y/N N
Horse Y/N N
Irrigation Water Rights Y/N N
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Interior
Flooring Carpet Concrete LuxuryVinylPlank
Basement (Y/N) N
Air Conditioning Y/N Y
Heating Y/N Y
Window Features DisplayWindows
Fireplace Y/N N
Total Baths 0
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Internal Only
Street Number 1 110
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* Excluded Features
List By
Sherry Traynum

Listing Agent

Howard Hanna Allen Tate/Pine To Palm Realty

Broker

Sherry@p2prealty.net

Email

Affordability Calculator

$15,753
Per Month
93%
7%
0%
Monthly Principal & Interest
$14,661
Monthly Property Taxes
$1,092
Monthly Home Insurance
--
Default based on a 30-year fixed rate of 6.375% with 20% down. The estimated payment is offered for convenience and is not an offer of credit. Due to market fluctuations, interest rates are subject to change at any time and without notice. Your individual rate may vary. Rates may differ for FHA, VA or jumbo loans.
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Nearby
329215 Elementary School
328947 Middle School
Unknown High School High School
Pricing History
DatePricePrice ChangeDescription
9/11/2025$2,350,000 Listed Price

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110 E Greenville Street, Anderson, SC, 29621 is a Commercial Property for sale at $2,350,000 with a lot size of 1.21. The property's zip code is 29621 which is in Anderson, SC